Course: Research in Modern Biology
Institute / University: National Institute of Pathology (NIP)
The Indian Registry of Pathology (IRP) was established in 1965 under the auspices of the Indian Council of Medical Research (ICMR) in New Delhi, India as a Centre for collection and distribution of teaching material in pathology. The Registry was renamed in 1980 as the National Institute of Pathology (IOP) in view of its expanded scope and activities. As per the need of the post-independence era when a large number of new medical colleges were coming up, IRP took up the initiative with the original aims and objectives of collection, classification, duplication and distribution of a representative spectrum of histo pathological teaching material to several medical colleges, institutions, individual pathologists and clinicians. Further, the Registry provided a consultative machinery through the medium of consultative panels for different branches of special pathology along with the gradual development of a training center for pathologists, technicians.
Original contributions of national importance have been made on many problems which are prevalent in the Indian subcontinent and where the pathogenesis of the disease was ill-understood. Special mention must be made of the contributions in the understanding of Indian Childhood Cirrhosis (ICC) and Non-Cirrhotic Portal Fibrosis (NCPF), neuropathology, osteopathology and pediatric pathology.
Research in Modern Biology
An innovative and cost-effective process of growing human epidermis in vitro has been identified and a patent filed from this laboratory. The process not only was proven to stimulate the proliferation of epidermal stem cells but could also be extended to other stem cells as well. Scaling up the production of fool-proof attenuated feeders using Bio reactor process is being considered. The preliminary clinical application of the cultured epidermis in burns patients yielded very encouraging results. Currently efforts are on to extend and upgrade the laboratory towards bringing out a specialized Pharmaceutical grade GMP facility suitable for the complex long-term culture technique of growing cultured epithelial auto grafts enabling larger trials in burns patients.
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